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PCOS vs PMDD: Distinguishing Mood and Hormonal Symptoms

PCOS vs PMDD: Distinguishing Mood and Hormonal Symptoms

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Living with hormonal health conditions can feel overwhelming, especially when trying to identify what's causing your symptoms. Two commonly confused conditions are Polycystic Ovary Syndrome (PCOS) and Premenstrual Dysphoric Disorder (PMDD). Though they share some similarities, understanding their differences is crucial for proper management and treatment.

What is PCOS?

Polycystic Ovary Syndrome is a complex hormonal disorder affecting about 1 in 10 women of reproductive age. It's characterized by an imbalance in reproductive hormones that can lead to multiple small cysts on the ovaries, irregular periods, excess androgen levels, and metabolic issues.

Key symptoms of PCOS include:

  • Irregular menstrual cycles or missed periods
  • Excess hair growth (hirsutism) on the face, chest, back
  • Acne and oily skin
  • Thinning hair or hair loss from the scalp
  • Weight gain, especially around the abdomen
  • Difficulty getting pregnant
  • Darkening of skin in neck creases, groin, underneath breasts
  • Skin tags
  • Mood changes, including depression and anxiety

PCOS symptoms are present throughout your cycle, though they may fluctuate in intensity. The condition is chronic and requires ongoing management, but with proper care, symptoms can be significantly reduced. Diet plays a crucial role in managing PCOS symptoms, with many finding relief by choosing grilled vs fried tofu and other anti-inflammatory foods.

What is PMDD?

Premenstrual Dysphoric Disorder is a severe form of premenstrual syndrome (PMS) that causes extreme mood shifts that can disrupt work and damage relationships. PMDD affects about 3-8% of women of reproductive age.

Key symptoms of PMDD include:

  • Severe mood swings, irritability, anger
  • Feelings of hopelessness or sadness
  • Extreme anxiety or tension
  • Difficulty concentrating
  • Fatigue and low energy
  • Food cravings or binge eating
  • Sleep problems (too much or too little)
  • Physical symptoms like breast tenderness, bloating, headaches
  • Feeling overwhelmed or out of control
  • Loss of interest in usual activities

Unlike PCOS, PMDD symptoms appear cyclically, typically starting 7-10 days before menstruation and improving within a few days after your period begins. This cyclical pattern is a key distinguishing feature.

PCOS vs PMDD: Key Differences

Timing and Duration of Symptoms

PCOS: Symptoms tend to be constant or persistent across your entire cycle, though they may fluctuate in severity.

PMDD: Symptoms follow a predictable pattern tied to your menstrual cycle, typically appearing during the luteal phase (after ovulation) and resolving shortly after menstruation begins.

Hormonal Differences

PCOS: Characterized by hormonal imbalances including high androgens (like testosterone), insulin resistance, and sometimes elevated estrogen with low progesterone.

PMDD: Believed to be caused by an abnormal response to normal hormone fluctuations, particularly sensitivity to changing levels of estrogen and progesterone. Overall hormone levels may be normal, but the body's response to these hormones is not.

Physical vs. Emotional Symptoms

PCOS: Primarily presents with physical symptoms (irregular periods, hair growth, acne, weight changes) with mood issues as secondary symptoms.

PMDD: Predominantly features severe mood and emotional symptoms, though physical symptoms can also occur.

Treatment Approaches

PCOS: Management focuses on lifestyle changes (diet, exercise), insulin-sensitizing medications, hormonal contraceptives, and addressing specific symptoms. Dietary choices like cauliflower rice vs fried rice and butter vs ghee can make a significant difference.

PMDD: Treatments include antidepressants (especially SSRIs), hormonal contraceptives, lifestyle modifications, and stress management techniques.

Can You Have Both PCOS and PMDD?

Yes, it's possible to have both conditions simultaneously. In fact, some research suggests women with PCOS may be more likely to experience severe PMS or PMDD symptoms. This could be due to the underlying hormonal imbalances in PCOS that may make some women more sensitive to normal cyclical hormone fluctuations.

When both conditions are present, symptoms can be particularly challenging to manage, as the hormonal fluctuations of PMDD can temporarily worsen some PCOS symptoms. Working with healthcare providers who understand both conditions is crucial.

Diagnosing PCOS vs PMDD

PCOS Diagnosis

Diagnosing PCOS typically involves:

  • Medical history and symptom evaluation
  • Physical examination
  • Blood tests to check hormone levels
  • Pelvic ultrasound to look for ovarian cysts

Doctors generally use the Rotterdam criteria, which requires at least two of the following three findings:

  1. Irregular or absent periods
  2. Clinical or biochemical signs of hyperandrogenism (excess male hormones)
  3. Polycystic ovaries on ultrasound

It's important to note that PCOS shares some symptoms with other conditions like Cushing's syndrome, so proper diagnosis is essential.

PMDD Diagnosis

Diagnosing PMDD involves:

  • Tracking symptoms for at least two menstrual cycles
  • Evaluating the timing and severity of symptoms
  • Ruling out other physical or psychiatric conditions

According to the DSM-5, PMDD diagnosis requires at least five symptoms during the week before menstruation, including at least one mood-related symptom. These symptoms must improve shortly after menstruation begins and cause significant distress or interference with daily functioning.

Managing PCOS and PMDD Through Diet

Both conditions can benefit from dietary modifications, though the specific approaches may differ slightly.

Dietary Strategies for PCOS

For PCOS, focus on:

Recipes like hormone support collagen beauty water or anti-inflammatory collagen golden milk can be beneficial.

Dietary Strategies for PMDD

For PMDD, consider:

  • Increasing complex carbohydrates (may help boost serotonin)
  • Calcium-rich foods (shown to reduce PMS symptoms)
  • Magnesium-rich foods (may help with mood and cramps)
  • Vitamin B6 foods (may help with mood symptoms)
  • Limiting caffeine, alcohol, and salt (especially during the luteal phase)
  • Small, frequent meals to maintain stable blood sugar

Eating plans featuring nutrient-dense vegetables and balanced hormone-supportive meals can help manage symptoms of both conditions.

Lifestyle Management Strategies

Beyond diet, several lifestyle factors can help manage both conditions:

Exercise

Regular physical activity benefits both conditions:

  • PCOS: Focus on a mix of cardio and strength training to improve insulin sensitivity and manage weight
  • PMDD: Emphasis on activities that boost mood and reduce stress, like yoga, walking, or swimming

Remember that altitude can affect PCOS symptoms, so adjust workout intensity accordingly if you live at higher elevations.

Stress Management

Stress can worsen both PCOS and PMDD symptoms. Effective strategies include:

  • Mindfulness meditation
  • Deep breathing exercises
  • Progressive muscle relaxation
  • Adequate sleep hygiene
  • Cognitive behavioral therapy techniques

Supplements

Some supplements may help with specific symptoms:

  • For PCOS: Inositol, N-acetylcysteine, omega-3 fatty acids, vitamin D
  • For PMDD: Calcium, magnesium, vitamin B6, chasteberry (Vitex)

Always consult with a healthcare provider before starting any supplement regimen.

Medical Treatments

PCOS Medical Treatments

  • Hormonal contraceptives to regulate periods and reduce androgen levels
  • Metformin or other insulin-sensitizing medications
  • Anti-androgen medications for hirsutism and acne
  • Fertility treatments when pregnancy is desired

PMDD Medical Treatments

  • Selective serotonin reuptake inhibitors (SSRIs), either daily or only during the luteal phase
  • Hormonal contraceptives, especially those containing drospirenone
  • GnRH agonists (for severe cases that don't respond to other treatments)
  • Anxiolytics for severe anxiety symptoms

Tracking Your Symptoms

For both conditions, but especially for distinguishing between PCOS and PMDD, symptom tracking is invaluable. Keep a daily log of:

  • Physical symptoms
  • Mood changes
  • Energy levels
  • Sleep quality
  • Food intake
  • Menstrual cycle dates

After 2-3 months, patterns usually emerge that can help you and your healthcare provider determine whether you're dealing with PCOS, PMDD, or both.

When to Seek Professional Help

Consult a healthcare provider if:

  • Your symptoms significantly impact your quality of life
  • You experience suicidal thoughts (seek immediate help)
  • You're unsure whether your symptoms indicate PCOS, PMDD, or another condition
  • Self-management strategies aren't providing adequate relief
  • You want to get pregnant but are having difficulties

Conclusion

While PCOS and PMDD can both cause significant physical and emotional symptoms, they are distinct conditions with different underlying causes, patterns, and treatment approaches. Understanding the key differences can help you advocate for proper diagnosis and treatment.

Many women successfully manage these conditions through a combination of lifestyle modifications, dietary changes, and medical treatments when necessary. Working with knowledgeable healthcare providers and listening to your body are key steps toward feeling better and regaining control over your hormonal health.

Extra Tip: Create a "symptom journal" specifically designed to distinguish between PCOS and PMDD. Use different colored pens or a digital app with color coding to track cyclical (PMDD) versus constant (PCOS) symptoms. This visual approach can make patterns more obvious and provide valuable information for your healthcare provider.

How This Article Was Made

This article was developed through comprehensive research of current medical literature and clinical guidelines. Information was gathered from reputable sources including:

The information presented aims to be current and evidence-based while remaining accessible. All dietary and supplement recommendations are supported by peer-reviewed research, though individual responses may vary.

Frequently Asked Questions About PCOS and PMDD

Can PCOS cause severe mood swings similar to PMDD?

Yes, PCOS can cause mood disturbances including depression and anxiety that may present as mood swings. However, the key difference is that PCOS-related mood issues tend to be more constant rather than following the cyclical pattern characteristic of PMDD. Women with PCOS may experience mood changes due to hormonal imbalances, insulin resistance, and the psychological impact of dealing with physical symptoms. If you're experiencing severe mood swings with PCOS, consider checking your complete symptom profile and tracking when they occur relative to your cycle to help distinguish the cause.

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How do I know if my symptoms are from PCOS, PMDD, or both?

The timing of your symptoms is the most critical factor in distinguishing between these conditions. Track your symptoms for at least 2-3 months, noting when they appear relative to your menstrual cycle. PMDD symptoms follow a predictable pattern that worsens before menstruation and improves within a few days after your period starts. PCOS symptoms tend to be more constant, though they may fluctuate in intensity. If you notice both patterns—some symptoms that are always present (like irregular periods, excess hair growth) plus severe mood symptoms that intensify before your period—you might have both conditions. A healthcare provider can help confirm through hormone testing, physical examination, and symptom evaluation.

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What foods should I avoid if I have both PCOS and PMDD?

If you're managing both conditions, focus on avoiding foods that may worsen symptoms of either disorder:

  • Highly processed foods and refined carbohydrates (affect insulin levels for PCOS and can worsen mood swings in PMDD)
  • Added sugars and artificial sweeteners (consider alternatives like date syrup instead of molasses)
  • Caffeine and alcohol (can exacerbate anxiety and sleep issues in both conditions)
  • High-sodium foods (can worsen PMDD-related bloating)
  • Dairy products for some individuals (consider trying vegan cheese alternatives or plant-based milks)
  • Foods high in saturated and trans fats (can increase inflammation)

Instead, prioritize anti-inflammatory whole foods, complex carbohydrates, lean proteins, and healthy fats. Recipes like hormone health fermented cashew cheese can be beneficial.

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Can birth control pills help with both PCOS and PMDD?

Yes, hormonal contraceptives are often prescribed for both conditions, though the specific formulations may differ. For PCOS, birth control pills can regulate menstrual cycles, reduce androgen levels, and improve symptoms like acne and excess hair growth. For PMDD, certain hormonal contraceptives, particularly those containing drospirenone, can help stabilize hormone fluctuations that trigger mood symptoms.

However, not all birth control formulations work equally well for both conditions. Some women with PMDD may find certain pills worsen their mood symptoms, while some women with PCOS may need specific formulations to address their hormonal imbalances. If you have both conditions, work closely with your healthcare provider to find the right hormonal treatment that addresses symptoms of both disorders. This may involve trying different formulations before finding the optimal one.

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How does stress affect PCOS and PMDD symptoms?

Stress can significantly worsen both PCOS and PMDD symptoms through several mechanisms:

For PCOS: Stress elevates cortisol levels, which can further disrupt hormone balance, increase insulin resistance, and promote abdominal fat storage. Chronic stress may also worsen inflammation, which plays a role in PCOS symptom severity.

For PMDD: Stress can amplify sensitivity to normal hormone fluctuations, intensifying emotional symptoms like irritability, anxiety, and mood swings. Stress also affects sleep quality, which can further exacerbate PMDD symptoms.

When you have both conditions, stress management becomes especially crucial. Effective stress reduction techniques include regular meditation, yoga, adequate sleep, setting boundaries, and potentially working with a mental health professional. Some women find that adaptogenic herbs help their bodies better manage stress responses. Dietary changes may also support better stress management, such as choosing appropriate snacks to stabilize blood sugar during stressful times.

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