About Thiazolidinediones
Thiazolidinediones such as Actos, Avandia, and Eulexin all can improve insulin resistance, which is a hurdle to losing weight for many women with PCOS. However, these drugs must be taken with birth control as they are highly contraindicated in pregnant women. These drugs have more side effects than many others, so you should discuss them with your doctor, carefully read package inserts, and weigh the pros and cons. They are a good option for some women, especially those that cannot lose weight with other means and are not planning a pregnancy in the near future.