Why Does Metformin Make Me So Tired with PCOS?

Why Does Metformin Make Me So Tired with PCOS?

Many women with PCOS (Polycystic Ovary Syndrome) take metformin to help manage insulin resistance and improve metabolic health. However, one common complaint is fatigue or extreme tiredness after starting metformin. Why does this happen, and what can you do about it?

Understanding Metformin Fatigue in PCOS

Metformin works by improving insulin sensitivity and reducing glucose production in the liver. While this helps lower blood sugar levels, it can also cause sudden energy crashes, especially if your body is adjusting to the medication.

Common Causes of Tiredness on Metformin

• Low Blood Sugar (Hypoglycemia): Metformin can sometimes cause blood sugar levels to drop too low, leading to weakness and fatigue.
• Vitamin B12 Deficiency: Long-term metformin use has been linked to vitamin B12 deficiency, which can cause tiredness, nerve problems, and brain fog. (Prenatal vitamins may help support B12 levels.)
• Digestive Issues: Some people experience gut disturbances on metformin, affecting nutrient absorption and leading to fatigue.
• Lactic Acidosis (Rare but Serious): In very rare cases, metformin can cause lactic acidosis, a condition where lactic acid builds up in the bloodstream, causing extreme weakness.

How to Reduce Fatigue from Metformin

• Eat Balanced Meals: Avoid blood sugar crashes by pairing carbohydrates with protein and healthy fats. (Try this PCOS-supporting protein pancake recipe.)
• Monitor Your B12 Levels: Consider taking a B12 supplement or eating more B12-rich foods like eggs, fish, and dairy.
• Stay Hydrated: Dehydration can worsen fatigue. Drink enough water and incorporate electrolyte-rich foods.
• Adjust Timing of Your Dose: Taking metformin with food or before bed may reduce side effects.
• Consider Alternatives: Some women find Ovasitol to be a gentler alternative to metformin.

Can Your Diet Help Manage Metformin Fatigue?

Yes! Eating an anti-inflammatory diet that stabilizes blood sugar can help reduce metformin-related fatigue. Some great choices include:

• Dandelion green and apple salad for blood sugar balance.
• Arugula and walnut pesto for hormone support.
• Collagen golden milk for reducing inflammation.

Should You Stop Taking Metformin?

If metformin fatigue is significantly affecting your life, speak with your doctor. They might adjust your dosage, switch to an extended-release version, or suggest other alternatives like intermittent fasting with metformin.

Final Thoughts

Metformin can be a helpful tool for PCOS management, but fatigue can be a frustrating side effect. By monitoring blood sugar, optimizing your diet, and considering supplements, you may be able to reduce tiredness and feel more energized.

How This Article Was Made

We reviewed studies from medical journals, reputable health sites, and government resources. Sources include the National Institutes of Health (NIH) and the American Diabetes Association. No information has been fabricated or taken from unreliable sources.